Genome editing has advanced at a rapid pace with promising results for treating genetic conditions — but there is always room for improvement. A new paper by investigators from Mass General Brigham published in Nature showcases the power of scalable protein engineering combined with machine…
Category: 5. Health
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New technique expands tissues so hundreds of biomolecules can be seen inside cells
For biologists, seeing is believing. But sometimes biologists have a hard time seeing.
One particularly vexing challenge is seeing all the molecules in an intact tissue sample, down to the level of single cells, simultaneously. Detecting the location of hundreds or thousands of biomolecules –…
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A repurposed anti-inflammatory drug may help treat alcohol use disorder and related pain
A preclinical study from scientists at Scripps Research finds that a drug already FDA-approved for treating inflammatory conditions may help reduce both alcohol intake and pain sensitivity — two issues that commonly co-occur with alcohol use disorder (AUD).
The results, published in JCI Insight…
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The most effective prevention method for complications post lung transplant
When receiving a lung transplant, one of the most important complications to look out for is chronic lung allograft dysfunction, known as CLAD.
Preventing this complication for those who receive a lung transplant is of the highest priority, as there are no universally effective treatments for…
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Obesity disrupts ‘reaction time’ to starvation in mice
Researchers led by Keigo Morita and Shinya Kuroda of the University of Tokyo have revealed a temporal disruption in the metabolism of obese mice when adapting to starvation despite no significant structural disruptions in the molecular network. This is a breakthrough discovery as research…
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Empowering antibodies to better activate the immune system
Antibodies are best known for their ability to latch onto and neutralize bacteria, viruses and other pathogens. But these immune proteins can do more than that: They also activate other components of the immune system, which then go to work to clear an infection. A new study from Scripps…
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Shining a light on DNA: A rapid, ultra-sensitive, PCR-free detection method
PCR genetic analysis has been in the spotlight since COVID-19, but light is now further facilitating PCR-free methods.
Osaka Metropolitan University scientists have developed a light-induced DNA detection technique, using heterogeneous probe particles, that enables ultra-sensitive and ultra-fast…
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Activity stabilizes mixtures | ScienceDaily
Asymmetric interactions between molecules may serve as a stabilizing factor for biological systems. A new model from researchers of the department Living Matter Physics at the Max Planck Institute for Dynamics and Self-Organization (MPI-DS) reveals this regulatory role of non-reciprocity. The…
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Retinal clues to mental health
The retina is part of the central nervous system and therefore a direct extension of the brain. This is why changes in the brain could potentially also be detected in our eyes. An international team of researchers led by the University of Zurich and the University Hospital of Psychiatry Zurich…
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Can hormone therapy improve heart health in menopausal women?
Deciding whether to start hormone therapy during the menopause transition, the life phase that’s the bookend to puberty and when a woman’s menstrual cycle stops, is a hotly debated topic. While hormone therapy, or replacing the hormones that were previously produced by the body with synthetic…
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