Osteoarthritis is the leading cause of disability and chronic pain worldwide, affecting an estimated 595 million people globally. Projections suggest that this number will rise to 1 billion by 2050. Despite its profound impact on individuals and societies, no disease-modifying treatments are…
Category: 5. Health
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Potential Alzheimer’s disease therapeutic target identified in brain immune cells
Tim-3 is an immune checkpoint molecule involved in immunity and inflammation recently linked to late-onset Alzheimer’s disease (AD), but its role in the brain was unknown until now. In a paper published in Nature, researchers from Mass General Brigham used preclinical models to uncover Tim-3’s…
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New gene editing tool shows promise for treating diseases with multiple mutations
Investigators from Mass General Brigham and Beth Israel Deaconess Medical Center have developed STITCHR, a new gene editing tool that can insert therapeutic genes into specific locations without causing unwanted mutations. The system can be formulated completely as RNA, dramatically simplifying…
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Your skin is breathing: New wearable device can measure it
Northwestern University researchers have developed the first wearable device for measuring gases emitted from and absorbed by the skin.
By analyzing these gases, the device offers an entirely new way to assess skin health, including monitoring wounds, detecting skin infections, tracking…
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Engineering smart delivery for gene editors
Modern genome editing techniques, including CRISPR systems, hold great potential for treating genetic diseases. However, delivering these molecular tools reliably to their target cells remains a significant challenge.
“Previous viral and non-viral delivery systems such as adeno-associated…
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‘Sugar’ signatures help identify and classify pancreatic cancer cell subtypes
Van Andel Institute scientists and collaborators have developed a new method for identifying and classifying pancreatic cancer cell subtypes based on sugars found on the outside of cancer cells.
These sugars, called glycans, help cells recognize and communicate with each other. They also act as…
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America’s Dependence On Foreign Medicine Is A Risk We Can’t Afford
Capsules moving on a conveyor at a pharmaceutical factory.
Although last week’s extensive tariff announcements exempted pharmaceuticals, President Trump has repeatedly maintained that he will eventually impose tariffs on the industry. The tariffs, touted as a remedy to our global…
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At The Brink Of Eradicating HIV, America Retreats From Heroism To Hesitation
Woman with Child
What an extraordinary moment in medical history: science has handed us the superpower to eradicate HIV/AIDS. Lenacapavir, a once-a-year injection, can treat HIV, prevent transmission, and stop new infections—all with a single shot. This breakthrough opens the…
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New AI Model Lets People Speak Using Only Their Thoughts
AI researchers have developed a neuroprosthesis for paralysis and stroke patients that ethically … More
Try to picture being completely conscious and mentally able — but not being able to speak. For people afflicted with…
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Americans die earlier at all wealth levels, even if wealth buys more years of life in the US than in Europe
Americans at all wealth levels are more likely to die sooner than their European counterparts, with even the richest U.S. citizens living shorter lives than northern and western Europeans. That is the key finding of our new study, published in the New England Journal of Medicine.
We also…
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