Scientists have attempted to map the human cell since the first microscope was invented more than 400 years ago. But many components of the cell still remain uncharted.
“We know each of the proteins that exist in our cells, but how they fit together to then carry out the function of a cell still…
Tim-3 is an immune checkpoint molecule involved in immunity and inflammation recently linked to late-onset Alzheimer’s disease (AD), but its role in the brain was unknown until now. In a paper published in Nature, researchers from Mass General Brigham used preclinical models to uncover Tim-3’s…
Investigators from Mass General Brigham and Beth Israel Deaconess Medical Center have developed STITCHR, a new gene editing tool that can insert therapeutic genes into specific locations without causing unwanted mutations. The system can be formulated completely as RNA, dramatically simplifying…
Northwestern University researchers have developed the first wearable device for measuring gases emitted from and absorbed by the skin.
By analyzing these gases, the device offers an entirely new way to assess skin health, including monitoring wounds, detecting skin infections, tracking…
Modern genome editing techniques, including CRISPR systems, hold great potential for treating genetic diseases. However, delivering these molecular tools reliably to their target cells remains a significant challenge.
“Previous viral and non-viral delivery systems such as adeno-associated…
Van Andel Institute scientists and collaborators have developed a new method for identifying and classifying pancreatic cancer cell subtypes based on sugars found on the outside of cancer cells.
These sugars, called glycans, help cells recognize and communicate with each other. They also act as…
Capsules moving on a conveyor at a pharmaceutical factory.
Although last week’s extensive tariff announcements exempted pharmaceuticals, President Trump has repeatedly maintained that he will eventually impose tariffs on the industry. The tariffs, touted as a remedy to our global…
Woman with Child
What an extraordinary moment in medical history: science has handed us the superpower to eradicate HIV/AIDS. Lenacapavir, a once-a-year injection, can treat HIV, prevent transmission, and stop new infections—all with a single shot. This breakthrough opens the…
AI researchers have developed a neuroprosthesis for paralysis and stroke patients that ethically … More
Try to picture being completely conscious and mentally able — but not being able to speak. For people afflicted with…
Americans at all wealth levels are more likely to die sooner than their European counterparts, with even the richest U.S. citizens living shorter lives than northern and western Europeans. That is the key finding of our new study, published in the New England Journal of Medicine.
We also…