A new study led by the Center for Sepsis Epidemiology and Prevention Studies (SEPSIS) at the Harvard Pilgrim Health Care Institute raises critical questions about the effectiveness of the Centers for Medicare and Medicaid Services’ (CMS) sepsis quality measure, known as the Severe Sepsis/Septic…
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Earliest stages and possible new cause of stomach cancer revealed
For the first time, scientists have systematically analysed somatic mutations in stomach lining tissue to unpick mutational processes, some of which can lead to cancer. The team also uncovered hints of a potential new cause of stomach cancer that needs further research.
Researchers at the…
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Machine learning aids in detection of ‘brain tsunamis’
A University of Cincinnati study found machine learning models can aid in the automation and detection of abnormal brain activity sometimes referred to as a “brain tsunami.”
UC’s Jed Hartings, PhD, is corresponding author of the study published March 12 in the journal Scientific Reports…
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Classifying childhood brain cancers by immune response may improve diagnostics and treatments
Researchers and pediatric neurosurgeons at the University of Pittsburgh School of Medicine and UPMC Children’s Hospital of Pittsburgh developed a new way to profile brain cancers in children, paving the way for improved diagnostics and treatments.
Today in Science Translational Medicine,…
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New understanding of B cell mutation strategies could have implications for vaccines
A vaccine’s ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a vaccine or pathogen, B cells scramble to refine their defenses, rapidly mutating in hopes of generating the most effective antibodies. But each round of this process is a roll…
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New mechanism behind adaptive immunity revealed: It could impact how we design vaccines
Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies through mutation and expansion until they produce high-affinity B cells adapted to keep different pathogens in check. But rapid evolution should come at a cost. Most mutations…
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Why are night owls at greater risk of depression?
Mindfulness, total sleep quality, and alcohol consumption may help explain why people who stay up late have a greater risk of depression, according to a new study publishing March 19, 2025, in the open-access journal PLOS One by Simon Evans of University of Surrey, UK, and colleagues.
Previous…
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Are you a night owl? You’re more at risk of depression. Here’s why
The early bird catches the worm, while the night owl is more at risk of developing depression. That’s according to a new study that suggests people who prefer waking up and staying up late are more likely to experience depressive symptoms, compared to early risers
A study by the University of…
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Israel launches ground operation to reoccupy corridor which splits Gaza in half
The Israeli military had previously withdrawn from the Netzarim Corridor, which it established, following a temporary ceasefire agreement with Hamas.
Israel has launched what it is calling a “limited ground operation” to retake part of the key Netzarim Corridor, the…
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Video. Fallas 2025: Valencia’s fireworks defy the rain
Valencia’s iconic firework spectacle, “La Nit del Foc” (the night of fire), dazzled crowds despite heavy rain, filling the night sky with colour, light, and sound. The Hermanos Caballer pyrotechnics team launched 1,405 kilos of fireworks in a breathtaking 20-minute display from the Jardines…
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