Scientists have long struggled to target proteins that lack defined structure and are involved in cancer, neurodegenerative disorders like Parkinson’s disease, and other serious illnesses. Now, a new study from Scripps Research demonstrates a proof of concept for a new strategy: engineering…
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Developing software for easy estimation of 3D gene expression distribution
Understanding the 3D spatial distribution of gene expression — in which a gene is active or inactive within biological tissue — is essential for uncovering gene functions. One method for estimating this distribution is RNA tomography, involving preparing frozen tissue sections along three…
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Revolutionizing protein modification: A new frontier in cancer research
A research team led by Professor Seung Soo Oh and Dr. Hyesung Jo from the Department of Materials Science and Engineering at POSTECH (Pohang University of Science and Technology) has developed an innovative technique that enables precise modification of specific proteins within complex…
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Preclinical study: After heart attack, a boost in anti-inflammatory cells promoted healing
A scientific technique that rapidly increases the body’s production of anti-inflammatory cells promoted healing from heart attacks in mice, according to a new study by investigators from the Smidt Heart Institute at Cedars-Sinai. Once adapted to treat humans, the technique could potentially be…
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Effects of multifunctional facility on daily walking time
Designing walkable neighborhoods has gained attention as a method to increase physical activity among urban populations. Moreover, highly walkable areas stimulate increased neighborhood retail sales, higher property values, and greater urban sustainability. However, only limited methods are…
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US national security scandal deepens as new Signal messages revealed
The Democrats have increased their calls for US Defence Secretary Pete Hegseth to resign for sending Yemen war plans via a messaging app.
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mRNA-based COVID-19 vaccines train the ‘long-term memory’ of the immune system
Researchers at the University of Cologne and University Hospital Cologne have shown in their study that the novel mRNA-based COVID-19 vaccines not only induce acquired immune responses such as antibody production, but also cause persistent epigenetic changes in innate immune cells. The study…
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Adulting is hard on the heart: Teen to young adulthood is a critical time to address risk
Many teenagers enter adulthood with significant risk factors for cardiovascular disease, and the transition from adolescence to adulthood is a key time to address these risk factors and reduce the risk of developing future cardiovascular disease, according to a new American Heart Association…
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Open-label placebos improve premenstrual syndrome
For many women, the days prior to menstruation are characterized by physical and mental suffering, with abdominal pain, nausea, mood swings, and anxiety. Almost half of women of reproductive age are affected by premenstrual syndrome (PMS), which restricts their everyday well-being and…
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Remember ebola?
Six years before the start of the COVID-19 pandemic, an Ebola outbreak in West Africa had people fearing the possibility of a global outbreak. This was the first time many had ever heard of the virus, but since it was first identified in 1976, there have actually been more than 20 serious Ebola…
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