A new study in the journal Nature explains how age reshapes the blood system. In both humans and mice, a few stem cells, or “clones,” outcompete their neighbours and gradually take over blood production. The blood stem cell reservoir shrinks and becomes dominated by clones which show a…
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Salivary gland regenerative biobank to combat chronic dry mouth
Millions of people are affected by chronic dry mouth, or xerostomia, an agonizing side effect of damaged salivary glands. While chemotherapy and radiation treatment for head and neck cancer are the most common causes of this, aging, certain medications and other factors, including diabetes,…
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This gene variant contributed to the dietary and physiological evolution of modern humans
Two of the traits that set modern humans apart from non-human primates are taller stature and a higher basal metabolic rate. Publishing in the Cell Press journal Cell Genomics on May 21, researchers have identified a genetic variant that contributed to the co-evolution of these traits. This…
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Ukrainian power broker shot dead in Spain – POLITICO
KYIV — Spanish police are investigating the death of Andrii Portnov, 51, a powerful Ukrainian former politician, who was living in Spain.
Portnov was shot dead by several unknown attackers on a street in Pozuelo de Alarcón, a town in the Madrid province of Spain, the…
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A new technology for extending the shelf life of produce
We’ve all felt the sting of guilt when fruit and vegetables go bad before we could eat them. Now, researchers from MIT and the Singapore-MIT Alliance for Research and Technology (SMART) have shown they can extend the shelf life of harvested plants by injecting them with melatonin using…
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Toothache from eating something cold? Blame these ancient fish
Anyone who has ever squirmed through a dental cleaning can tell you how sensitive teeth can be. This sensitivity gives important feedback about temperature, pressure — and yes, pain — as we bite and chew our food. However, the sensitive parts inside the hard enamel first evolved for something…
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Common antidepressants could help the immune system fight cancer
A widely used antidepressant drug could help the immune system fight cancer, according to a new UCLA research study.
Selective serotonin reuptake inhibitors, or SSRIs, significantly enhanced the ability of T cells to fight cancer and suppressed tumor growth across a range of cancer types in both…
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Newfound mechanism rewires cellular energy processing for drastic weight loss
Mice genetically engineered to lack the ability to make the amino acid cysteine, and fed a cysteine-free diet, lost 30 percent of their body weight in just one week, a new study shows.
Published online May 21 in Nature, the work found that cysteine depletion disrupts the normal metabolic…
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Scientists design gene delivery systems for cells in the brain and spinal cord
Research teams funded by the National Institutes of Health (NIH) have created a versatile set of gene delivery systems that can reach different neural cell types in the human brain and spinal cord with exceptional accuracy. These delivery systems are a significant step toward future precise gene…
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Live view: Stress-induced changes in generations of cancer cells
Cancer cells respond to stress with greater diversity. Drugs that affect DNA replication, or radiation that causes direct DNA damage, lead to increasingly diverse offspring over multiple cell generations. This increases the tumor’s genetic complexity and facilitates the development of resistance…
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